Abiraterone Acetate for CRPC CAS:154229-18-2 CAS NO.154229-18-2

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Min.Order: 1 Kilogram
Payment Terms: T/T

Product Details

Keywords

Abiraterone acetate
154229-18-2
Abiraterone Acetate factory

Quick Details

ProName: Abiraterone Acetate for CRPC CAS:15422...
CasNo: 154229-18-2
Molecular Formula: C26H33NO2
Appearance: Off-White to Pale Yellow Solid
Application: anti-cancer
DeliveryTime: promptly/ in stock
PackAge: 25kgs packaging Fiber drum outside and...
Port: Shanghai
ProductionCapacity: 100 Metric Ton/Month
Purity: 99%
Storage: in stock/promptly
Transportation: fedex, DHL, Other express company, by ...
LimitNum: 1 Kilogram
Related Substances: according to COA
Residue on Ignition: according to COA
Heavy Metal: according to COA
Valid Period: inquiry

Superiority

Overview

Quick Details

CAS No.:: 154229-18-2

Other Names:: Abiraterone Acetate

MF:: C26H33NO2

EINECS No.:: NO

Place of Origin:: Shaanxi, China (Mainland)

Type:: Abiraterone Acetate

Grade Standard:: Food Grade

Usage:: Animal Pharmaceuticals

Brand Name:: YR

Model Number:: API

Purity:: 99%

Product Name:: Abiraterone Acetate

Appearance:: white crystalline powder

Shelf life:: 2 Years

Packing:: Drum, Plastic Container

Packaging & Delivery

Packaging Details: 25kgs packaging Fiber drum outside and plastic bag inside 1-25kgs packaging aluminium bag outside and double plastic bag inside.
Delivery Detail: within 3 days when get the payment

Delivery Time: 3 days when get the payment

Details

Abiraterone Acetate for CRPC CAS:154229-18-2

Description

English name: Abiraterone acetate

Synonyms:Abirateroneacetate;CB 7630;(3β)-17-(pyridin-3-yl)androsta-5,16-dien-3-yl acetate

Specification: 98%

CAS NO.:154229-18-2

Appearance: White crystalline powder

Molecular weight: 391.55

Molecular formula:C26H33NO2

Introduction

Abiraterone acetate, the active ingredient of ZYTIGA is the acetyl ester of abiraterone. Abiraterone is an inhibitor of CYP17 (17α-hydroxylase/C17,20-lyase). Each ZYTIGA tablet contains 250 mg of abiraterone acetate. Abiraterone acetate is designated chemically as (3β)-17-(3-pyridinyl)androsta-5,16-dien-3-yl acetate

Abiraterone acetate is a white to off-white, non-hygroscopic, crystalline powder. Its molecular formula is C26H33NO2and it has a molecular weight of 391.55. Abiraterone acetate is a lipophilic compound with an octanol-water partition coefficient of 5.12 (Log P) and is practically insoluble in water. The pKa of the aromatic nitrogen is 5.19.

Inactive ingredients in the tablets are colloidal silicon dioxide, croscarmellose sodium, lactose monohydrate, magnesium stearate, microcrystalline cellulose, povidone, and sodium lauryl sulfate.

Function

Abiraterone is a drug used in castration-resistant prostate cancer. It is formulated as the prodrug abiraterone acetate. Abiraterone can be used as a prostate cancer drug treatment. Abiraterone is a inhibitor of CYP17. It can be used to treat CRPC.

COA

Items	Specifications	Results
Appearance	White or off white crystalline powder	white crystalline powder
Identification	The retention time of the major peak in the chromatogram of the test preparation corresponds to that in the chromatogram of the reference preparation	Complies
Related Substance	Single impurity ≤0.5% Total impurity ≤1.0%	0.28% 0.32%
Moisture	≤0.5%	0.11%
Residue on ignition	≤0.1%	0.02%
Heavy metal	≤10ppm	Complies
Assay (dry basis)	Not less than 99.0% (HPLC)	99.7%
Conclusion: The product conforms to the In-house standard